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CFS in TCM theory The primary symptoms of CFS align closely with the TCM term “Deficiency Fatigue.” As early as during the Eastern Han Dynasty, Zhang Zhongjing discussed this condition in “ Essential Prescriptions of the Golden Coffer .” Additionally, symptoms such as palpitations, insomnia, anxiety, and depression fall under categories like “constraint” and “organ agitation.” Throughout history, TCM practitioners have attributed the causes of this condition to be multifaceted: 1) it may stem from congenital insufficiency leading to deficiencies in organs, qi , blood, yin and yang

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[DOI] [PMC free article] [PubMed] [Google Scholar] 38.Oluwayiose OA, Wu H, Saddiki H, Whitcomb BW, Balzer LB, Brandon N, et al